THE RÔLE OF FIBER SIZE IN THE ESTABLISHMENT OF A NERVE BLOCK BY PRESSURE OR COCAINE

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Abstract
An important factor, determining the relative susceptibility of the constituent fibers in a nerve trunk to a pressure and to cocaine, is their size. Pressure exerts its greatest effect on the large fibers, cocaine upon the small ones. There is evidence in the literature that the sensations of contact, temp., and pain are blocked in this order by pressure; and in the reverse order by cocaine. The 2 sets of observations, therefore, indicate the location of these functions among the fiber groups.