Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats
- 1 January 1998
- journal article
- research article
- Published by Wolters Kluwer Health in PAIN®
- Vol. 75 (2) , 261-272
- https://doi.org/10.1016/s0304-3959(98)00004-9
Abstract
There are few pharmacological studies of central neuronal measures in animal models of neuropathic pain. In the present study we have compared the effects of two anticonvulsants, carbamazepine and gabapentin, on spinal neuronal responses of nerve injured rats (selective ligation of spinal neKeywords
This publication has 24 references indexed in Scilit:
- Inflammation reveals inhibition of noxious responses of rat spinal neurones by carbamazepineNeuroReport, 1997
- The effects of mexiletine, desipramine and fluoxetine in rat models involving central sensitizationPain, 1997
- Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors.Proceedings of the National Academy of Sciences, 1996
- Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic painPain, 1995
- Painful neuropathy: altered central processing maintained dynamically by peripheral inputPain, 1992
- An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the ratPain, 1992
- Onset of a painful peripheral neuropathy in rat: a partial and differential deafferentation and spontaneous discharge in A beta and A delta primary afferent neuronsJournal of Neurophysiology, 1992
- Chronic pain: a PET study of the central effects of percutaneous high cervical cordotomyPain, 1991
- Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the ratBrain Research, 1990
- The effect of intravenous lidocaine, tocainide, and mexiletine on spontaneously active fibers originating in rat sciatic neuromasPain, 1989