False-Positive Histoplasma capsulatum Gen-Probe Chemiluminescent Test Result Caused by a Chrysosporium Species

Abstract
We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-reactivity with a respiratory isolate thought to be Histoplasma but not morphologically consistent with H. capsulatum . The isolate was later identified as the Chrysosporium anamorph of Nannizziopsis vriesii by sequence analysis and phenotypic data.