Techniques And Application Of FTIR Vibrational Circular Dichroism
- 1 December 1989
- proceedings article
- Published by SPIE-Intl Soc Optical Eng
- Vol. 1145, 57-64
- https://doi.org/10.1117/12.969374
Abstract
Vibrational Circular Dichroism (VCD) has proven to be useful for detecting conformational change and for characterizing secondary structures for a variety of biopolymers. Use of FTIR-based VCD for such problems has been made possible with recent improvements in optical design and S/N. FTIR-VCD and dispersive VCD each have strengths that are optimal for specific problems. A comparison of techniques is presented in this lecture, and selected examples of VCD applications to polypeptides and proteins are given.Keywords
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