Meta-analysis of haplotype-association studies: comparison of methods and empirical evaluation of the literature
Open Access
- 1 January 2011
- journal article
- research article
- Published by Springer Nature in BMC Genetics
- Vol. 12 (1) , 8
- https://doi.org/10.1186/1471-2156-12-8
Abstract
Meta-analysis is a popular methodology in several fields of medical research, including genetic association studies. However, the methods used for meta-analysis of association studies that report haplotypes have not been studied in detail. In this work, methods for performing meta-analysis of haplotype association studies are summarized, compared and presented in a unified framework along with an empirical evaluation of the literature.This publication has 115 references indexed in Scilit:
- Association of the GNAS locus with severe malariaHuman Genetics, 2008
- Evaluation of a Susceptibility Gene for Schizophrenia: Genotype Based Meta-Analysis of RGS4 Polymorphisms from Thirteen Independent SamplesBiological Psychiatry, 2006
- Evaluating associations of haplotypes with traitsGenetic Epidemiology, 2004
- Combination of direct and indirect evidence in mixed treatment comparisonsStatistics in Medicine, 2004
- The role of haplotypes in candidate gene studiesGenetic Epidemiology, 2004
- Algorithms for inferring haplotypesGenetic Epidemiology, 2004
- The International HapMap ProjectNature, 2003
- On the advantage of haplotype analysis in the presence of multiple disease susceptibility allelesGenetic Epidemiology, 2002
- Advanced methods in meta‐analysis: multivariate approach and meta‐regressionStatistics in Medicine, 2002
- Meta-analysis in clinical trialsControlled Clinical Trials, 1986