A Phase I Trial of Intravenous CG7870, a Replication-Selective, Prostate-Specific Antigen–Targeted Oncolytic Adenovirus, for the Treatment of Hormone-Refractory, Metastatic Prostate Cancer
Open Access
- 1 July 2006
- journal article
- research article
- Published by Elsevier in Molecular Therapy
- Vol. 14 (1) , 107-117
- https://doi.org/10.1016/j.ymthe.2006.02.011
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Ablating CAR and Integrin Binding in Adenovirus Vectors Reduces Nontarget Organ Transduction and Permits Sustained Bloodstream Persistence Following Intraperitoneal AdministrationMolecular Therapy, 2004
- TNFerade Biologic, an Adenovector With a Radiation-Inducible Promoter, Carrying the Human Tumor Necrosis Factor Alpha Gene: A Phase I Study in Patients With Solid TumorsJournal of Clinical Oncology, 2004
- Prostate cancer updateCurrent Opinion in Oncology, 2003
- Phase II Trial of Intravenous CI-1042 in Patients With Metastatic Colorectal CancerJournal of Clinical Oncology, 2003
- Intravascular adenoviral agents in cancer patients: Lessons from clinical trialsCancer Gene Therapy, 2002
- Phase I Trial of Intraperitoneal Injection of the E1B-55-kd-Gene-Deleted Adenovirus ONYX-015 (dl1520) Given on Days 1 Through 5 Every 3 Weeks in Patients With Recurrent/Refractory Epithelial Ovarian CancerJournal of Clinical Oncology, 2002
- Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activityGene Therapy, 2001
- Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancerOncogene, 2000
- Pre-Existent Adenovirus Antibody Inhibits Systemic Toxicity and Antitumor Activity of CN706 in the Nude Mouse LNCaP Xenograft Model: Implications and Proposals for Human TherapyHuman Gene Therapy, 2000
- Cytokines in adenoviral disease in children: Association of interleukin-6, interleukin-8, and tumor necrosis factor alpha levels with clinical outcomeThe Journal of Pediatrics, 1994