Charge-Migration Phenomena in γ-Irradiated Costacking Complexes of DNA Nucleotides: II. An ESR Study of Various Complexes in Frozen Solution
- 1 March 1979
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 77 (3) , 417-431
- https://doi.org/10.2307/3575154
Abstract
The radiochemistry of various complexes formed by the costacking association of different DNA nucleotides in frozen solution was investigated using the appropriate computer-assisted techniques. The existence of important charge migration phenomena was revealed in all the nucleotide complexes. Positive charges migrate toward guanine, while negative charges migrate toward cytosine. The experimental data obtained are consistent with the assumption that electron affinity increases in the order G < A < T < C, with the converse true for electron donor properties. This leads to a large excess of cytosine anions and guanine cations and subsequently to the selective distribution of secondary radicals on the same constituents. The radiochemistry of heterogeneous systems containing DNA bases in a stacking configuration cannot be considered to be simply the sum of the radiochemistries of the constituent subunits.This publication has 3 references indexed in Scilit:
- Free Radical Formation in Deoxyguanosine-5′-Monophosphate γ-Irradiated in Frozen Solution. A Computer-Assisted Analysis of Temperature-Dependent ESR SpectraRadiation Research, 1977
- Charge Migration Phenomena in γ-Irradiated Costacking Complexes of DNA Nucleotides: I. A Computer-Assisted ESR Analysis of dAMP · dTMP Complexes in Frozen SolutionRadiation Research, 1977
- Free-Radical Formation in Deoxythymidine-5′-Monophosphate γ-Irradiated in Frozen Solution. A Computer-Assisted Analysis of Temperature-Dependent ESR SpectraRadiation Research, 1976