Caveolae: From Cell Biology to Animal Physiology
Top Cited Papers
- 1 September 2002
- journal article
- review article
- Published by Elsevier in Pharmacological Reviews
- Vol. 54 (3) , 431-467
- https://doi.org/10.1124/pr.54.3.431
Abstract
Among the membrane compartments of a cell, vesicles known as "caveolae" have long defied functional characterization. However, since the identification of a family of proteins termed "caveolins", that form and reside in caveolae, a better understanding has emerged. It is now clear that caveolae do not merely play a singular role in the cell, but are pleiotropic in nature-serving to modulate many cellular functions. The purpose of this review is to explicate what is known about caveolins/caveolae and highlight growing areas of caveolar research.Keywords
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