Effects of Ammonia Inhalation on Respiration Rate of Rabbits
- 1 March 1972
- journal article
- Published by Oxford University Press (OUP) in Journal of Animal Science
- Vol. 34 (3) , 448-452
- https://doi.org/10.2527/jas1972.343448x
Abstract
The effect of ammonia inhalation on respiration rate was studied in 16 New Zealand White rabbits held under controlled environmental conditions. Exposure to 50 ppm and 100 ppm ammonia for 2.5 to 3 hr. significantly decreased (P<.01) respiration rate 34.0% and 32.3%, respectively, compared to control conditions. The periodicity of relative changes in respiratory volume was not significantly affected by ammonia exposure; however, apparent depth of respiration increased during this period. In determinations on five animals, blood urea nitrogen was increased from 19.4 to 24.6 mg/100 ml (P<.005) and blood CO2 increased from 14.3 to 18.9 meq/liter plasma (P<.07) as a result of animal exposure to 100 ppm ammonia. Blood pH was not significantly affected. Postmortem examination revealed no pathological changes in lungs, liver, spleen or kidneys which could be attributed to the effects of short period exposures to ammonia. Copyright © 1972. American Society of Animal Science . Copyright 1972 by American Society of Animal Science.Keywords
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