The Complications of Age-Related Macular Degeneration Prevention Trial (CAPT): rationale, design and methodology

Abstract
Background The Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) is a randomized clinical trial to evaluate whether prophylactic laser treatment to the retina can prevent the complications of the advanced stage of Age-Related Macular Degeneration (AMD), the leading cause of irreversible blindness.