ESTROGEN PRODUCTION BY THE TESTIS*†

Abstract
Evidence is presented to substantiate the findings of others that in the dog,feminizing testicular tumors exist which appear to be composed of Sertoli cells and which are rich in lipids and produce considerable quantities of estrogen. This evidence combined with that of others in humans in which estrogen production appears to be related to the presence of Sertoli cells forms the basis for the postulate that the 2d hormone of the testis is an estrogen produced by Sertoli cells.
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