Treatment of Solid P815X2 Murine Mastocytoma With Adriamycin (NSC-123127): Toxicity Limitations 2
- 1 March 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 56 (3) , 683-685
- https://doi.org/10.1093/jnci/56.3.683
Abstract
The efficacy of adriamycin (NSC-123127), given as weekly or as 5-day-per-week doses, on the control of solid P815X2 murine mastocytomas was severely limited by hematopoietic and gastrointestinal toxicity. Although daily or weekly drug schedules both elicited dose responsiveness in terms of tumor control, no dose level of drug increased the life-span of tumor-bearing animals.Keywords
This publication has 1 reference indexed in Scilit:
- Quantitative colonial growth of mammalian cells in fibrin cellsExperimental Cell Research, 1964