The Search for Erythropoietin

Abstract
Studies of the regulation of red-cell production have recently taken on some urgency because of the potential usefulness of erythropoietin in the treatment of patients with anemia due to chronic renal disease. For such treatment, far greater amounts of erythropoietin will be needed than can be supplied from serum and urine, and it is necessary to go to the source of production to meet the demand. Since the classic study by Jacobson and his co-workers in 1957,1 it has generally been accepted that the source of production must be the kidney. The kidney is assumed to have a dual erythropoietic . . .

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