HISTOLOGIC AND ELECTRON-MICROSCOPIC LIVER CHANGES IN DIABETIC CHILDREN

  • 1 January 1979
    • journal article
    • research article
    • Vol. 26  (6) , 435-438
Abstract
The results of 99 histologically examined liver biopsy samples, 14 of them also examined under the EM taken from 68 insulin-treated diabetic children of both sexes at an age from 2-14 yr, most of them with long-standing diabetes, are presented, thus giving a survey of morphologic liver findings of diabetes mellitus in this age group. Apart from metabolic changes, such as amount of fat and glycogen storage, including the nuclear glycogen of the liver, secondary diseases of inflammatory nature play a prominent role in 1/3 of the children. There are definite correlations with the degree of metabolic decompensation, demanding preventive and therapeutic measures.

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