Skin Temperature and Blood Flow Changes in Occlusive Arterial Disease Under Physical and Pharmacologic Therapy* t

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Abstract
Experiment-ally blood flow and skin temperature parallel each other, which is known to occur in the low blood flow range. There is a considerable variability of blood flow in vascular patients due to some factors which cannot be sufficiently controlled. There are, for instance, spontaneous Increases in skin temperature lasting for hours after the patient has been placed in the examining room which prevent a steady state''s being reached. If these variables, especially the spontaneous increase in blood flow, are taken into account, one cannot postulate significant effects of nicotinlc acid, ATP, and connective tissue massage as judged by skin blood flow and temperature measurements of the acral portions ol the affected limbs. In chronic experiments there are slight changes in the response to indirect heating which point to the possibility of a beneficial effect of long-term treatment with connective tissue massage.

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