Über blutgerinnungshemmende Substanzen
Open Access
- 1 October 1946
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung A
- Vol. 1 (10) , 584-591
- https://doi.org/10.1515/zna-1946-1009
Abstract
Among the sulfuric acid esters of polymeric-homologous series, those of unbranched celluloses and polyvinyl alcohols are very effective in checking blood-coagulation, whereas the branched starch and spheric glycogen-esters were far less, or not at all effective. In unbranched products, checking effect decreases little, toxic-ity increases essentially with increasing mol. wt. The greatest effect and least toxicity occur in filiform molecules with polymerization of 20-80 degrees. Xylansulfuric acid ester proved a highly effective and nearly atoxic substance, already applied successfully in acute thrombosis.This publication has 1 reference indexed in Scilit:
- Zur Kenntnis blutgerinnungshemmender Polysaccharid‐poly‐schwefelsäure‐ester und ähnlicher VerbindungenHelvetica Chimica Acta, 1943