Depletion of Plasma Hemopexin in Man by Hematin Injections
- 1 June 1969
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 131 (2) , 371-373
- https://doi.org/10.3181/00379727-131-33880
Abstract
Repeated intravenous injections of hematin in a normal human subject produced depletion of the plasma heme-binding β-globulin, hemopexin. The observations provide support for the hypothesis that hemopexin depletion in hemolytic disease is due to its binding of heme and consequent shortened survival in the circulation.Keywords
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