Ventilatory Pattern during Handgrip in Normal Man

Abstract
We studied the ventilatory response to an isometric handgrip (50% maximum voluntary contraction) in 7 young normal subjects. VE increased significantly during isometric contraction due to increases in Vt/Ti (the mean inspiratory flow) and Ti/Ttot (the timing component of ventilation). The increase in Vt/Ti is greater than that in Ti/Ttot; thus, the contribution of the neural inspiratory drive is predominant in increasing the pulmonary ventilation during a handgrip.

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