ABNORMAL ALPHA KETOSTEROID EXCRETION IN PATIENTS WITH NEOPLASTIC DISEASE

16 June 1944

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 99 (2581) , 494-496
https://doi.org/10.1126/science.99.2581.494

Abstract

Urinary [alpha]-ketosteroids were fractionated systematically by chromatographic adsorption analysis. The crystalline products were purified and characterized. Graphs were constructed showing the pattern of [alpha]-ketosteroid distribution in normal urine and its contrast with abnormal patterns from patients with lymphatic leukemia and cancer. It is uncertain whether the abnormalities are specific for the particular disorder studied.