Statistical Analysis of Renal Clearance by the Dog.*

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Abstract
From data accumulated over a 6-yr. period on 31 trained, unanesthetized female dogs the following mean values for several renal functions were calculated: glomerular filtration rate (creatinine clearance) = 94 cc./min./sq. m. surface area; renal plasma flow (p-aminohippurate clearance following its oral admn.) = 238 cc./min./sq. m.; p-aminohippurate Tm = 16.5 mg./min./sq. m.; arginine Tm = 12.9 mg./min./sq. m.; simultaneous (creatinine) GF/p-aminohippurate RPF filtration fraction = 0.40; and GF/penicillin RPF "filtration fraction" = 0.35. A statistical analysis of the results was presented.

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