Abstract
A phenomenological analysis of the general two Higgs doublet model is presented. Possible constraints of the Yukawa couplings result from the K0K0, B0B0, and D0D0 mixings. It is shown that the emerging of various new sources of CP violation in the model could strongly affect the determination of the unitarity triangle. It could be useful to look for a signal of new physics by comparing the extracted angle β from two different ways, such as from the process BJ/ψKS and from fitting the quantities |Vub|, ΔmB, and ε.