THE EFFECTS OF HIGH FAT DIETS AND COLD ENVIRONMENT ON THE ASCORBIC ACID CONTENT OF THE BROWN ADIPOSE TISSUE

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Abstract
At room temperature, the ascorbic acid content of the brown adipose tissue is doubled when rats are fed a high fat diet. It is nevertheless lower than in tissues studied by others under somewhat similar conditions. In cold adapted rats, the brown body is considerably hypertrophied and the ascorbic acid content is from four to eight times higher than at room temperature. Under our experimental conditions, rats exposed to cold doubled the weight of their perirenal fat with little or no change in total body weight. It is concluded that cold stimulates fat metabolism and that both ascorbic acid and the brown adipose tissue are involved in the process.