Acute Leukemia in Pregnancy

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Abstract
ACUTE leukemia is not rare in adults of reproductive age. With the advent of increasingly effective chemotherapeutic regimens, 62% of patients with leukemia from 20 to 34 years of age can be expected to obtain complete remission. The median anticipated length of survival presently exceeds 60 weeks, and we hope this will improve rapidly.1Therefore, the management of leukemia during pregnancy will require increasing attention. Management decisions are difficult, and data are sparse. One important consideration is the potential effect of chemotherapy on the fetus. Two women received intensive chemotherapy and achieved remission while carrying pregnancies to term. Report of Cases Case 1.— A 22-year-old woman, gravida 2 and para 1, was admitted to the University Hospital on Sept 14, 1973, with a three-week history of increasing weakness and melena. She was approximately four months pregnant according to history. At the time of admission, she had a temperature of 38.7

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