Abstract
Voltage-capacity curves of single frog muscle fibers were detd. after soaking in iced normal Ringer''s for 24 hrs. The fibers then were microinjected with small amounts of isosmotic solns. of either trisodium citrate, sodium oxalate or secondary sodium phosphate and the curves redetermined; the curves were uniformly shifted toward higher threshold values. The discrepancy between the sensitizing effects of extracellular decalcification and the above findings is stressed and interpretation is discussed.

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