O-benzyl hydroxyproline as a bioisostere for Phe-Pro: Novel dipeptide thrombin inhibitors

This publication has 15 references indexed in Scilit:

• Chapter 8. Anticoagulant Strategies Targeting Thrombin and Factor Xa
  Published by Elsevier ,1995
• Direct thrombin inhibitors in cardiovascular medicine.
  Circulation, 1994
• Superior Activity of a Thromboxane Receptor Antagonist as Compared with Aspirin in Rat Models of Arterial and Venous Thrombosis
  Journal of Cardiovascular Pharmacology, 1993
• Lasting safe interruption of endarterectomy thrombosis by transiently infused antithrombin peptide D-Phe-Pro-ArgCH2Cl in baboons
  Blood, 1993
• Refined 2·3ÅX-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA: A starting point for improving antithrombotics
  Journal of Molecular Biology, 1992
• The refined 1.9‐Å X‐ray crystal structure of d‐Phe‐Pro‐Arg chloromethylketone‐inhibited human α‐thrombin: Structure analysis, overall structure, electrostatic properties, detailed active‐site geometry, and structure‐function relationships
  Protein Science, 1992
• Pharmacologic Aspects of the Development of Selective Synthetic Thrombin Inhibitors as Anticoagulants
  Seminars in Thrombosis and Hemostasis, 1992
• Thrombin structure and function
  Blood Coagulation & Fibrinolysis, 1991
• Thrombin^a
  Annals of the New York Academy of Sciences, 1986
• D-PHE-PRO-ARGCH2Cl-A selective affinity label for thrombin
  Thrombosis Research, 1979