Transmission of New Bovine Prion to Mice
Open Access
- 1 July 2006
- journal article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 12 (7) , 1125-1128
- https://doi.org/10.3201/eid1207.060107
Abstract
We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrPres). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrPres molecular features distinct from BSE.Keywords
This publication has 14 references indexed in Scilit:
- Primary Isolation of the Bovine Spongiform Encephalopathy Agent in Mice: Agent Definition based on a Review of 150 TransmissionsJournal of Comparative Pathology, 2005
- Discrimination between Scrapie and Bovine Spongiform Encephalopathy in Sheep by Molecular Size, Immunoreactivity, and Glycoprofile of Prion ProteinJournal of Clinical Microbiology, 2004
- Identification of a second bovine amyloidotic spongiform encephalopathy: Molecular similarities with sporadic Creutzfeldt-Jakob diseaseProceedings of the National Academy of Sciences, 2004
- Distinct molecular phenotypes in bovine prion diseasesEMBO Reports, 2004
- Molecular Analysis of the Abnormal Prion Protein during Coinfection of Mice by Bovine Spongiform Encephalopathy and a Scrapie AgentJournal of Virology, 2001
- Similarity of the lesion profile of BSE in Portuguese cattle to that described in British cattleVeterinary Record, 2000
- Molecular analysis of prion strain variation and the aetiology of 'new variant' CJDNature, 1996
- BSE in Great Britain: consistency of the neurohistopathological findings in two random annual samples of clinically suspect casesVeterinary Record, 1996
- Bovine spongiform encephalopathy: a new disease of cattle?Published by Springer Nature ,1993
- Transmission of bovine spongiform encephalopathy and scrapie to miceJournal of General Virology, 1992