Propionibacterium acnes Immunotherapy in Chronic Recurrent Canine Pyoderma
- 1 January 1989
- journal article
- clinical trial
- Published by Wiley in Journal of Veterinary Internal Medicine
- Vol. 3 (1) , 26-30
- https://doi.org/10.1111/j.1939-1676.1989.tb00325.x
Abstract
In a randomized, double-blind, placebo-controlled study, dogs with chronic recurrent pyoderma were treated with antibiotics plus intravenous injections of either Propionibacterium acnes or placebo. Responses (an increase, decrease, or clearing of lesions) were measured and evaluated statistically. Eighty percent (12 of 15) of the dogs treated with antibiotics and P acnes compared with 38% (five of 13) of the dogs treated with antibiotics and placebo responded with significant improvement or complete remission of lesions at the end of the 12-week treatment schedule (P less than 0.05).Keywords
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