Transforming Potential of Human c- sis Nucleotide Sequences Encoding Platelet-Derived Growth Factor
- 10 August 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 225 (4662) , 636-639
- https://doi.org/10.1126/science.6740330
Abstract
The nucleotide sequence of a transforming human c- sis complementary DNA shows an open reading frame 723 base pairs in length located downstream from an in-phase terminator thymine-guanine-adenine codon. Sequences within this region were identical to those previously determined for the exons of the normal human c- sis gene. Thus, the predicted transforming product, a protein of 27,281 daltons, may be the actual precursor for normal human platelet-derived growth factor chain A.This publication has 31 references indexed in Scilit:
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