EXPERIMENTAL HYDRONEPHROSIS

1 November 1925

journal article
research article
Published by American Medical Association (AMA)

Vol. 11 (5) , 649-659
https://doi.org/10.1001/archsurg.1925.01120170002001

Abstract

The effects on the rate of development of hydronephrosis of an increase in blood flow and blood pressure, brought about by unilateral splanchnotomy have been described¹with the conclusion that the rate of urinary secretion as affected by this procedure influences very little, if at all, its ordinary rate of development with complete ureteral obstruction. Partial compression of one renal artery will produce the opposite effect—permanent unilateral oliguria. When the renal artery is partially compressed, there is a diminished blood flow and a diminished intrarenal blood pressure which together reduce the amount of urine secreted and lower the maximal back pressure with ureteral obstruction. What interference will this change have on the rate of development of hydronephrosis? Herman,²as early as 1862, studied the effect of this procedure on urine secretion. He employed a screw clamp by means of which he was able to vary the compression, and

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