IMMUNIZATION AGAINST VACCINIA BY NON-INFECTIVE MIXTURES OF VIRUS AND IMMUNE SERUM
Open Access
- 1 February 1931
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 53 (2) , 185-193
- https://doi.org/10.1084/jem.53.2.185
Abstract
1. Vaccine virus and specific immune serum mixed in such proportions as to produce no lesion when inoculated intradermally induce immunity when instilled into the nasal cavities of rabbits. 2. The mixture is also effective when inoculated subcutaneously. 3. Immunity is brought about with a minimum of systemic reaction and no local one. 4. When the mixtures are incompletely neutralized generalized vaccinia results.Keywords
This publication has 1 reference indexed in Scilit:
- A STUDY OF THE GENERALIZATION OF VACCINE VIRUS FROM ENHANCED SKIN LESIONSThe Journal of Experimental Medicine, 1929