Ethical Issues in Studies in Thailand of the Vertical Transmission of HIV

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Abstract
In response to the controversy over placebo-controlled trials in developing countries of treatments to prevent mother-to-child transmission of the human immunodeficiency virus (HIV),1 I would like to offer the perspective of someone who lives and works in Thailand, a developing country with limited resources that is the site of several such trials.Placebo-Controlled Trials in Developing CountriesI believe that placebo-controlled trials are sometimes justified in countries where treatment is otherwise totally unavailable, because at least half the patients (those receiving active treatment) will probably benefit. This is particularly true if the trial will generate results that will directly benefit . . .