Über die Wirkung von 5-Oxo-6-diazo-norleucin und Albizziin auf die Biosynthese der Anthranilsäure inSaccharomyces cerevisiae

Abstract
A tryptophan auxotroph of S. cerevisiae, which accumulates anthranilic acid, produces chorismic acid in the presence of 6-diazo-5-oxonorleucine. A phe, tyr- mutant of S. cerevisiae also releases chorismic acid into the medium upon the addition of 6-diazo-5-oxonorleucine. Al-buizziin(2-amino-3-ureidopropionic acid) exerts the same action. In the presence of 6-diazo-5-oxonorleucine, the wild strains of S. cerevisiae and Escherichai coll release 4-hydroxybenzoic acid and phenylpyruvic acid into the medium.

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