Fittig bislactones in cyclopentenone synthesis: short synthesis of methylenomycin B
- 15 October 1982
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 60 (20) , 2528-2530
- https://doi.org/10.1139/v82-363
Abstract
Treatment of the Fittig bislactone, 3-(1,1-dihydroxypropyl)glutaric acid di-γ-lactone, with methyllithium, followed by alkali, afforded 5-carboxymethyl-2,3-dimethylcyclopent-2-en-1-one. This compound on decarboxylation with lead tetraacetate afforded the antibiotic methylenomycin B.This publication has 0 references indexed in Scilit: