Evaluation of Dubos' Solid Medium Containing Penicillin in the Isolation of Tubercle Bacilli.
- 1 April 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 70 (4) , 589-592
- https://doi.org/10.3181/00379727-70-17004
Abstract
Of 300 clinical specimens 134 were positive for tubercle bacilli on Dubos'' solid oleic acid-albumin medium containing 100 U./cc. of penicillin, and 120 were positive on a standard egg-potato medium. Without the presence of penicillin to restrain contaminants, only 91 cultures were positive on the Dubos medium. The Dubos medium was also considered satisfacotry because of the ease with which growth could be observed on the transparent agar, and because of the characteristic cord-like appearance of virulent tubercle bacilli, which apparently distinguishes them from avirulent tubercle bacilli, and from other organisms.Keywords
This publication has 3 references indexed in Scilit:
- Effect of Penicillin on the Tubercle Bacillus In vitro.Experimental Biology and Medicine, 1947
- VIRULENCE AND MORPHOLOGICAL CHARACTERISTICS OF MAMMALIAN TUBERCLE BACILLIThe Journal of Experimental Medicine, 1947
- Submerged Growth of Tubercle Bacilli from Pathologic Material in Dubos' MediumExperimental Biology and Medicine, 1946