Oligothymidylates: Formation by Thermal Condensation of O 2 ,5′-Cyclothymidine 3′-Phosphate
- 21 July 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 177 (4045) , 272-274
- https://doi.org/10.1126/science.177.4045.272
Abstract
Thermal activation of O2,5'-cyclothymidine 3'-phosphate in solution and in the solid state led to the formation of thymidine oligonucleotides containing up to approximately 12 nucleotide units. Only the 3',5' internucleotide diester bonds were formed. This polymerization occurs without the addition of any activating agent or catalyst.Keywords
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