Survival functions induced by stochastic covariate processes
- 1 June 1981
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of Applied Probability
- Vol. 18 (02) , 523-529
- https://doi.org/10.1017/s0021900200098193
Abstract
A vector X of patient prognostic variables is modeled as a linear diffusion process with time-dependent, non-random, continuous coefficients. The instantaneous force of mortality (hazard function) operating on the patient is assumed to be a time-dependent, continuous quadratic functional of the prognostic vector. Conditional on initial data X 0, the probability of surviving T units of time is expressed in terms of the solution of a Riccati equation, which can be evaluated in closed form if the coefficients of the process and the hazard are constant. This conditional expectation does not preserve proportional hazards.Keywords
This publication has 3 references indexed in Scilit:
- A time-dependent statistical model which relates current clinical status to prognosis: Application to advanced prostatic cancerJournal of Chronic Diseases, 1980
- A random-walk model of human mortality and agingTheoretical Population Biology, 1977
- The Wiener Measure of Hilbert Neighborhoods in the Space of Real Continuous FunctionsJournal of Mathematics and Physics, 1944