Cytochrome P-450 Oxidations and the Generation of Biologically Reactive Intermediates
- 1 January 1991
- book chapter
- Published by Springer Nature
- Vol. 283, 1-11
- https://doi.org/10.1007/978-1-4684-5877-0_1
Abstract
No abstract availableKeywords
This publication has 40 references indexed in Scilit:
- Low kinetic hydrogen isotope effects in the dehydrogenation of 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester (nifedipine) by cytochrome P-450 enzymes are consistent with an electron/proton/electron transfer mechanismChemical Research in Toxicology, 1990
- Cytochrome P-450 catalysis: radical intermediates and dehydrogenation reactionsTrends in Pharmacological Sciences, 1989
- Alkene epoxidations catalyzed by iron(III), manganese(III), and chromium(III) porphyrins. Effects of metal and porphyrin substituents on selectivity and regiochemistry of epoxidationJournal of the American Chemical Society, 1989
- Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylaseBiochemistry, 1987
- Mechanism of cytochrome P-450 catalysis. Mechanism of N-dealkylation and amine oxide deoxygenationJournal of the American Chemical Society, 1985
- Oxidation of sparteines by cytochrome P-450: evidence against the formation of N-oxidesJournal of Medicinal Chemistry, 1984
- Composition of cytochrome P‐450 isozymes from hepatic microsomes of C57BL/6 and DBA/2 mice assessed by warfarin metabolism, immunoinhibition, and immunoelectrophoresis with anti‐(rat cytochrome P‐450)European Journal of Biochemistry, 1984
- Electron transfer from nitrogen in microsomal oxidation of amine and amide. Simulation of microsomal oxidation by anodic oxidationJournal of the American Chemical Society, 1982
- Destruction of cytochrome P-450 by vinyl fluoride, fluroxene, and acetylene. Evidence for a radical intermediate in olefin oxidationBiochemistry, 1982
- Enzymatic monooxygenation of halogen atoms: cytochrome P-450 catalyzed oxidation of iodobenzene by iodosobenzeneJournal of the American Chemical Society, 1980