Use of immobilized synthetic peptides for the identification of contact sites between human interleukin‐6 and its receptor

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Abstract
Synthetic peptides immobilized on cellulose membranes proved to be a powerful tool for the identification of sites in the cytokine IL-6 involved in receptor binding. Similarly, a region in the extracellular part of the IL-6 receptor which is important for interaction with its ligand was identified