Bladder sensory desensitization decreases urinary urgency
Open Access
- 11 June 2007
- journal article
- research article
- Published by Springer Nature in BMC Urology
- Vol. 7 (1) , 9
- https://doi.org/10.1186/1471-2490-7-9
Abstract
Bladder desensitization has been investigated as an alternative treatment for refractory detrusor overactivity. Most open and controlled clinical trials conducted with intravesical RTX showed that desensitization delays the appearance of involuntary detrusor contractions during bladder filling and decreases the number of episodes of urgency incontinence.Keywords
This publication has 38 references indexed in Scilit:
- The molecular basis of urgency: regional difference of vanilloid receptor expression in the human urinary bladderNeurourology and Urodynamics, 2007
- Effect of Intravesical Resiniferatoxin (RTX) on Lower Urinary Tract Symptoms, Urodynamic Parameters, and Quality of Life of Patients with Urodynamic Increased Bladder SensationEuropean Urology, 2006
- Therapeutic Effect of Multiple Resiniferatoxin Intravesical Instillations in Patients With Refractory Detrusor Overactivity: A Randomized, Double-Blind, Placebo Controlled StudyJournal of Urology, 2006
- Urodynamic Effect of Intravesical Resiniferatoxin in Patients with Neurogenic Detrusor Overactivity of Spinal Origin: Results of a Double-Blind Randomized Placebo-Controlled TrialEuropean Urology, 2005
- USING THE CIRCUMSTANCES OF SYMPTOM EXPERIENCE TO ASSESS THE SEVERITY OF URGENCY IN THE OVERACTIVE BLADDERJournal of Urology, 2005
- P2X3-Immunoreactive Nerve Fibres in Neurogenic Detrusor Overactivity and the Effect of Intravesical Resiniferatoxin*1European Urology, 2004
- Parallel changes in bladder suburothelial vanilloid receptor TRPV1 and pan‐neuronal marker PGP9.5 immunoreactivity in patients with neurogenic detrusor overactivity after intravesical resiniferatoxin treatmentBJU International, 2004
- Current and Future Pharmacological Treatment for Overactive BladderJournal of Urology, 2002
- Topography of the Vanilloid Receptor in the Human Bladder: More Than Just the Nerve FibersJournal of Urology, 2002
- Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1Nature Neuroscience, 2002