Detection of an Antigen Associated with Acute Leukemia
- 10 December 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 174 (4014) , 1136-1137
- https://doi.org/10.1126/science.174.4014.1136
Abstract
Antiserums to a purified cell membrane component from a Burkitt's lymphoma tissue culture cell line were produced in rabbits. These antiserums were cytotoxic to peripheral white blood cells from 8 of 15 patients with acute leukemia and 5 of 41 relatives, but not to peripheral white blood cells from leukemia patients in clinical remission or from normal individuals. These antiserums appear to be detecting an acute leukemia associated antigen or antigens.Keywords
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