Asymmetric Synthesis of Substituted Isoxazolidinone from α,β-Unsaturated Esters and Hydroxylamines by means of Double Stereodifferentiation
- 1 November 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (11) , 1171-1173
- https://doi.org/10.1055/s-1995-5228
Abstract
Asymmetric synthesis of isoxazolidinones (1) has been developed by Michael addition and ensuing transesterification processes employing chiral hydroxylamines and α,β-unsaturated esters carrying chiral α-hydroxycarboxylic acid ester unit as an alkoxide moiety.Keywords
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