A Stereoselective α-Hydroxylation of Cyclohexanecarbonitriles
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 6 (6) , 447-451
- https://doi.org/10.1080/00397917608065594
Abstract
The traditional approach to the synthesis of cyanohydrins from carbonyl compounds was augmented by a recent approach involving the α-hydroxylation of nitriles.1 Each synthetic method possesses certain limitations and yet offers distinct advantages in scope.2 Although both methods provide useful syntheses of cyanohydrins of cyclohexanones, it was of interest to contrast the stereoselectivity of the nitrile and ketone approach in cyclohexyl systems.Keywords
This publication has 10 references indexed in Scilit:
- FROM THE LITERATUREMedical Reference Services Quarterly, 2006
- Organoselenium chemistry. .alpha.-Lithio selenoxides and selenides. Preparation and further transformation to olefins, dienes, and allylic alcoholsJournal of the American Chemical Society, 1975
- Oxidative decyanation of secondary nitriles via .alpha.-hydroperoxynitrilesThe Journal of Organic Chemistry, 1975
- A synthetic method for direct conversion of ketones into cyanides. Introduction of a one carbon unit.Tetrahedron Letters, 1973
- Polyphenylnaphtalenes, especially 1,4,5,8-tetraphenylnaphthaleneTetrahedron, 1964
- Stereospecific Elimination Reactions with Cyclic Ketone Cyanohydrins.Acta Chemica Scandinavica, 1964
- 271. Alkylcyclohexanone cyanohydrinsJournal of the Chemical Society, 1964
- The Conformational Preference of the Cyano Group1The Journal of Organic Chemistry, 1962
- Über die synthese von oligophenylenes mit einer o‐verknüpfung. 10. MitteilungDie Makromolekulare Chemie, 1960
- The Condensation of trans-1-Phenyl-1,3-butadiene with Acrylonitrile, Acrylyl Chloride, Acrylamide and Propiolic Acid1Journal of the American Chemical Society, 1952