FURTHER STUDIES IN THE PHARMACOLOGY OF THE HEART OF CANCER MAGISTER DANA
- 1 April 1942
- journal article
- research article
- Published by University of Chicago Press in The Biological Bulletin
- Vol. 82 (2) , 255-260
- https://doi.org/10.2307/1538075
Abstract
The effects of nicotine, muscarine, curare, deryl and mecholyl on the crab heart are discussed. Nicotine did not exhibit its usual excitatory effect after atropini-zation of the heart. The effect of muscarine was similar to that of nicotine but is abolished by atropine. Curare brings about diastolic stoppage and abolished or profoundly modified the response of the heart to acetylcholine. Deryl and mecholyl produced excitatory effects but those of the latter were abolished by atropine. A previously proposed hypothetical mediation mechanism is reexamined in the light of these results.This publication has 1 reference indexed in Scilit:
- ACETYLCHOLINE AND NERVOUS INHIBITION IN THE HEART OF VENUS MERCENARIAThe Biological Bulletin, 1940