Effect of Tablet Lubricants on Axial and Radial Work of Failure
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 8 (3) , 445-453
- https://doi.org/10.3109/03639048209022111
Abstract
During diametral compression and axial tensile strength testing force-displacement curves were obtained for tablets of microcrystalline cellulose. The area under the curve, termed work of failure, was determined by planimetry. For each of the five lubricants studied as the concentration of the lubricant was increased in the tablet, the work of failure was considerably less. The effect was especially marked in the axial plane.Keywords
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