Using Chemopreventive Agents to Enhance the Efficacy of Cancer Therapy
Open Access
- 1 April 2006
- journal article
- review article
- Published by American Association for Cancer Research (AACR) in Cancer Research
- Vol. 66 (7) , 3347-3350
- https://doi.org/10.1158/0008-5472.can-05-4526
Abstract
Emerging evidence suggests that cancer preventative agents might be combined with chemotherapy or radiotherapy for the more effective treatment of cancer. Recent studies suggest that genistein and other dietary compounds that prevent cancer may enhance the efficacy of cancer therapeutics by modifying the activity of key cell proliferation and survival pathways, such as those controlled by Akt, nuclear factor-κB, and cyclooxygenase-2. In this article, we summarize the findings of recent investigations of chemopreventive agents in combination with cancer treatment regimens. (Cancer Res 2006; 66(7):3347-50)Keywords
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