A Longitudinal and Comparative Study of the Soft Tissue Calcium Levels Throughout the Life-Span of Highly Inbred Rats
- 1 April 1973
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Gerontology
- Vol. 28 (2) , 143-151
- https://doi.org/10.1093/geronj/28.2.143
Abstract
This study establishes the tissue calcium levels at progressive ages in two strains of highly inbred rats having different normal life-spans. An attempt is made to correlate the length of life with the alterations of calcium content in II tissues from short-lived Fischer and longer-lived A × C rats. Tissue calcium was determined by atomic absorption spectrophotometry. The tissue calcium changes generally occurred at an earlier chronological age in the shorter-lived rats, but comparisons between the two strains at comparable physiological ages revealed few significant strain differences. These findings suggest that even though qualitatively similar changes occur in both rat strains, the longerlived rats can more effectively maintain tissue calcium levels with the passage of time.Keywords
This publication has 1 reference indexed in Scilit:
- Bone Electrolytes in the Aging RatJournal of Gerontology, 1969