Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes
- 1 June 1996
- journal article
- research article
- Published by Elsevier in Journal of Chromatography B: Biomedical Sciences and Applications
- Vol. 681 (2) , 233-239
- https://doi.org/10.1016/0378-4347(96)00043-6
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1Biochemical Pharmacology, 1995
- Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomesChemical Research in Toxicology, 1994
- Evidence That Cytochrome-P450 2E1 Is Involved in the (ω-1)-Hydroxylation of Lauric Acid in Rat Liver MicrosomesBiochemical and Biophysical Research Communications, 1994
- Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniquesBiochemical Pharmacology, 1993
- Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazoneChemical Research in Toxicology, 1993
- Role of cytochrome P4502E1 in alcoholic liver disease pathogenesisAlcohol, 1993
- Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspectsChemical Research in Toxicology, 1991
- Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1Chemical Research in Toxicology, 1990
- Induction of laurate ω-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomesBiochemical and Biophysical Research Communications, 1984
- Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid)Biochemical Journal, 1982