DEMONSTRATION OF 16α-HYDROXYLASE IN THE HUMAN OVARY*†
- 1 November 1961
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 21 (11) , 1376-1383
- https://doi.org/10.1210/jcem-21-11-1376
Abstract
The presence of 16[alpha]-hydroxylase in the human ovary was demonstrated by conversion of 4-C14-progesterone to 16a-hydroxyprogesterone in incubations with tissue minces. Increased 16-hydroxylase activity was found in tissues abundant in follicular and thecal elements. There is suggestive evidence that Stein-Leventhal ovarian tissue contains more enzymatic activity than does normal ovarian tissue.Keywords
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