RADIOACTIVE IODINE IN THE TREATMENT OF HYPERTHYROIDISM

1 January 1951

journal article
research article
Published by American Medical Association (AMA) in Archives of internal medicine (1960)

Vol. 87 (1) , 4-16
https://doi.org/10.1001/archinte.1951.03810010014002

Abstract

HERTZ AND Roberts¹ in 1942 published the first report of patients treated with radioactive iodine. Although the results are difficult to interpret because of the almost simultaneous administration of I¹²⁷, their work forms a landmark in the medical application of the radioactive isotopes to the treatment of disease. Early studies on both thyroid physiology and treatment of thyroid disease were accomplished by the use of the 12 hour isotope I¹³⁰.² In 1946 the availability of radioactive isotopes from the uranium chain-reacting pile was announced, and easy accessibility of the eight day isotope was made possible. The fact that I¹³⁰ would be displaced in treatment by I¹³¹ was recognized by Soley when he stated at the meetings of the American Goiter Association in 1949, "I have omitted the use of I¹³⁰. the 12.5 hour isotope, because probably it will no longer have a role in this type of

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