The Effects of ACTH and of Cortisone on the Platelets in Idiopathic Thrombopenic Purpura

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Abstract
THE following case reports illustrate the dramatic effects of ACTH and of cortisone on the platelets in 3 patients with idiopathic thrombopenic purpura.Case ReportsCase 1. C. I. (No. 13998), a 59-year-old woman, was first admitted to the Massachusetts General Hospital in March, 1945, with idiopathic thrombopenic purpura of several years' duration. Because of increasing purpura a splenectomy was performed, with marked improvement. In January, 1946, the patient underwent an uncomplicated cholecystectomy for cholelithiasis. She suffered no recurrent symptoms until the summer of 1950, when petechiae and later ecchymoses developed over her legs and trunk. For two months prior . . .

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